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Huffs n Puffs | Cannabis Industry News and Insights
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    Social Equity Partners founder Thomas Lopez Looks to Empower Cannabis Entrepreneurs through Community Investment

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    Every person is different and therefore the effects they feel after consuming cannabis are different too. For some, marijuana is a lovely getaway from reality; for others, it's nothing more than a source of side effects like paranoia, cognitive problems or an increased risk of developing schizophrenia.Until now, it wasn't clear as to which specific regions of the brain were responsible for these highly divergent effects of cannabis. However, a new study -- led by Steven Laviolette, Ph.D., Professor at Western's Schulich School of Medicine & Dentistry and Christopher Norris, a postdoctoral fellow -- reveals critical new insights into how marijuana can produce such highly diverse psychological effects in different individuals.The researchers wrote in their study that translational rodent research helped them identify specific target regions in the brain that 'apparently' independently control rewarding, addictive properties of marijuana versus the psychiatric side-effects associated with its consumption.What exactly did the study find?The researchers noted that THC -- the psychoactive chemical in marijuana -- produced highly rewarding effects in the front-most part of an area of the brain called the nucleus accumbens. Furthermore, it was seen, the cannabinoid amplified the addictive properties of opioid drugs such as morphine and "increased reward-related activity patterns in the neurons".On the other hand, THC in the posterior area of the nucleus accumbens region produced highly adverse effects which included schizophrenia-related emotional and cognitive symptoms, and patterns of neuron activity similar to those found in people suffering from this serious mental illness.The researchers concluded: "Since the reward and aversion are produced by anatomically distinct regions, the different effects experienced by individuals is likely because of genetic variation leading to differential sensitivity of each regions."Here's the link to the study published in the journal Scientific Reports

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    Michigan: Tier-oriented fee system introduced for legal marijuana businesses

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    Florida legalizes cannabis edibles for medical marijuana patients

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    adolescent marijuana use not linked with structural brain difference finds study

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    Every person is different and therefore the effects they feel after consuming cannabis are different too. For some, marijuana is a lovely getaway from reality; for others, it's nothing more than a source of side effects like paranoia, cognitive problems or an increased risk of developing schizophrenia.Until now, it wasn't clear as to which specific regions of the brain were responsible for these highly divergent effects of cannabis. However, a new study -- led by Steven Laviolette, Ph.D., Professor at Western's Schulich School of Medicine & Dentistry and Christopher Norris, a postdoctoral fellow -- reveals critical new insights into how marijuana can produce such highly diverse psychological effects in different individuals.The researchers wrote in their study that translational rodent research helped them identify specific target regions in the brain that 'apparently' independently control rewarding, addictive properties of marijuana versus the psychiatric side-effects associated with its consumption.What exactly did the study find?The researchers noted that THC -- the psychoactive chemical in marijuana -- produced highly rewarding effects in the front-most part of an area of the brain called the nucleus accumbens. Furthermore, it was seen, the cannabinoid amplified the addictive properties of opioid drugs such as morphine and "increased reward-related activity patterns in the neurons".On the other hand, THC in the posterior area of the nucleus accumbens region produced highly adverse effects which included schizophrenia-related emotional and cognitive symptoms, and patterns of neuron activity similar to those found in people suffering from this serious mental illness.The researchers concluded: "Since the reward and aversion are produced by anatomically distinct regions, the different effects experienced by individuals is likely because of genetic variation leading to differential sensitivity of each regions."Here's the link to the study published in the journal Scientific Reports

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Cannabis Tinctures: All you should know

by Raghav
April 24, 2019
in Knowledge
0
Cannabis tinctures facts and things to know

image source: GreenState

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One of the most precise ways of consuming medical marijuana is through tinctures. For those who are not aware of what tinctures are- Tinctures are basically medicines made by dissolving a drug in alcohol. They usually contain a high %age of alcohol and come in glass bottles with droppers.

Tinctures are often regarded as one of the best, yet most underrated, delivery methods for cannabis. The dropper ensures precise doses with minimal effort. Nonetheless, not many people are familiar with its usage, despite its origin dating back well before the pre-Prohibition era.

Here is everything that you must know about tinctures:

Quick relief

Tinctures are generally consumed by placing a few drops beneath the tongue, a procedure better known as the sublingual administration. This method is a boon for those who want rapid relief from their symptoms/condition, with minimum effort.

The tissues under the tongue start absorbing the medicine into the arterial system as soon as the drops are placed. All you need to do is just sit back and wait for the desired effects to take over.

Tinctures have stood the test of time

Cannabis tinctures were present even when there was no aspirin. In fact, they were widely used before cannabis was prohibited.

Notably, cannabis-infused extracts (tinctures) were listed in the U.S. Pharmacopeia as a treatment for several conditions, including tonsillitis, tetanus, gout, menstrual cramps, alcoholism, cholera, arthritis, etc.

Green-Flower reports that patented cannabis tinctures were even sold over the counter in the early 20th century.

Are great topicals

Since cannabis topicals have a lot of filler and very low cannabinoid content, they sometimes fail to deliver what they promise.

Alternatively, tinctures are highly effective even when used as topicals. Although not much research is available to support the claim, many anecdotal accounts point towards the deduction that acid cannabinoid (THCA and CBDA) tinctures can help treat muscle sprains, bruises, sunburns, psoriasis and many other skin conditions.

The different kinds

Cannabis tinctures are flexible, that is, it is not necessary for them to contain alcohol. They can very well have olive oil, glycerin, MCT oil, etc. as the solvent.

Although there is some debate in the cannabis world regarding which type of tincture is the best, you certainly can’t go wrong with olive oil in terms of health and better shelf life.

Tinctures provide many options

Depending on the kind of cannabinoid(s) you require for treating your condition, you can opt from a wide variety of cannabis tinctures. There are dedicated CBDA, CBD, THC, THCA, etc. tinctures available for purchase depending on the legality of cannabis in your state.

Low in Calorie

If obesity and weight-gain are one of your biggest health concerns and you are still consuming cannabis via edibles like infused sweets and brownies, then we think you should switch over to tinctures.

Notably, a cannabis-infused brownie may boast up to 170 (or more) calories. Therefore, tinctures are a better low-calorie alternative.

Odorless & Unnoticeable

Some people are shy when it comes to using marijuana. They want to keep it low-key and feel embarrassed when others notice them consuming it even if it’s for medicinal purpose. Therefore, a cannabis tincture is perhaps one of the best solutions for this group.

Furthermore, since tinctures do not produce any noticeable odor, feel free to use them at any place without the fear of bothering others.

Sometimes when using a dropper is not an option, patients can insert their tincture solution into gelatin capsules. Swallowing your tincture, however, isn’t similar to placing the drops under your tongue as it has now become an edible and will take a longer time to bring relief than it was originally intended.

Tinctures need care

Darkness, cold temperature and airtight glass containers are the three pre-requisites to maintain a cannabis tincture, as heat and light have the tendency to destroy cannabinoids.

Wondering if plastic can be used to store tinctures?

No, you should never use any plastic container for your tinctures as it can compromise the infusions over time.

Efficient cannabinoid and terpene absorption

As stated earlier, the sublingual administration of tinctures puts the medicine directly into your bloodstream, as opposed to ingesting which takes relatively longer.

Hence, with tinctures, the positive effects can be felt within just 15 minutes, lasting at least 2-3 hours. Also note that if the tincture is well-made, you’ll get a much more efficient cannabinoids/terpene absorption rate than via any other consumption method.

The Bottom Line

Given that cannabis tinctures can come in handy for so many purposes, it’s better to at least give it a try and make a transition from other methods of consumption, like smoking, vaping, edibles, etc.

mm

Raghav

A writer during the day; a philosopher during the night, your 'Highness'!

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